Effect of Cinnamon Zeylanicum on serum Testosterone and anti-oxidants levels in Rats

Objectives: Cinnamon as an antioxidant is able to reduce oxidative stress. Previous study confirmed antioxidant enzymes have beneficial and essential effects on male infertility by their role against reactive oxygen species. Material and methods: Wistar male rats (n=20) were allocated into two groups, control group (n=10) and cinnamon group (n=10) that received 75mg/kg by gavage method, daily for 4 weeks respectively while the control group just received an equal volume of distilled water daily. In 30th day, 5 cc blood sample of each rat was taken for testosterone measurement. Results: Total serum testosterone and TAC (total antioxidant capacity) levels were significantly increased in group that has received 75mg/kg cinnamon in comparison to control group (P<0.05). It was not seen any significant difference between groups in testis weight. Conclusion: Since in our study 75mg/kg Cinnamon has significantly increased serum testosterone and TAC, it seems to use it in infertile patients has beneficial effects. 1-Department of Pharmacognosy, Tabriz University of medical sciences, Tabriz-Iran. 2-Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. ARTICLE HISTORY: Received March 2013 Accepted April 2013 Available online May 2013 Corresponding Author: Arash khaki, Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Tel: +984115541221 Email: [email protected]